The paradoxes of organ transplantation.

The significance of determining the therapeutic dose of cyclosporine-A in patients undergoing organ transplantation

Immunosuppressive drugs are now unavoidibly used after the transpantation of liver,heart and bone marrow, as well as in certain autoimmune diseases.among these agents,cyclosporine-A (CYA) is one of the most effective Immunosuppressants which is widely used.but as any Immunosuppressive agent,the use of CYA is not without harmful side effects.neurotoxin,nephrotoxic and hepatotoxic complications,m...

A Study on Information Sources of Patients Receiving Organ Transplantation

Objective Access to quality information is essential for greater patient participation in treatment. This study aims to investigate the information sources of organ transplant recipients in Mashhad, Iran. Methods This analytical cross-sectional study was carried out from December 2017 to May 2018. Participants were 115 patients who received liver and kidney transplantation in Montaseriyeh Hosp...

Complications of Organ Transplantation

Bioethics of organ transplantation.

As the ability to transplant organs and tissues has grown, the demand for these procedures has increased as well--to the point at which it far exceeds the available supply creating the core ethical challenge for transplantation--rationing. The gap between supply and demand, although large, is worse than it appears to be. There are two key steps to gaining access to a transplant. First, one must...

Immunopathology of Organ Transplantation

The early history of transplantation is born of legends. The Saints Cosmas and Damian, who lived in the third century allegedly, treated a white patient by removing one of his legs and by grafting that of a black man who had died the same day (Figure 1.1) (1). In modern times, many experimental transplantations, mostly in dogs and cats and then in humans, were attempted in the twenties and thir...